Novel Bio-fabrication Modelling Approach from Marine Sources: Synthesis, Characterization and its Composite Formulations

Authors

  • Gunarajulu Renganathan Division of Biomedical Engineering, Department of ECE, Anna University, Chennai 600025, India Author
  • R. Dheivanai Division of Biomedical Engineering, Department of ECE, Anna University, Chennai 600025, India Author
  • Kalyani Durai Division of Biomedical Engineering, Department of ECE, Anna University, Chennai 600025, India Author
  • Suguna Lakshmi Madurai Polymer Science and Technology Division, CSIR-Central Leather Research Institute, Chennai 600020, India Author

Keywords:

hydroxyapatite, bone tissue engineering, composite scaffold, seashells

Abstract

Hydroxyapatite, a bone mineral was extracted from different seashell species by hydrothermal method and investigated by SEM-EDX, FTIR, TGA, DSC, XRD, and EPR analysis. Amongst, the seashell Dallarca subrostata was chosen for composite preparation by incorporating chitosan and silver nanoparticles which could be used as fillers and films for wound healing applications. Silver ions doped HA were examined using EPR for better biocompatibility. These findings further aim to create a patient-specific implant using 3D modelling. It paves the way for the potential applications as a pre-operative surgical planning procedure and a better point of health care. Further, the biominerals extracted would act as a source for the fabrication of designs and thereafter 3D modelling for investigation. It also rectifies tissue engineering challenges faced so far.

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Published

2022-02-23

Issue

Vol. 36 No. S1 (2022)

Section

Original Research Article