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Hydroxyapatite, a bone mineral was extracted from different seashell species by hydrothermal method and investigated by SEM-EDX, FTIR, TGA, DSC, XRD, and EPR analysis. Amongst, the seashell Dallarca subrostata was chosen for composite preparation by incorporating chitosan and silver nanoparticles which could be used as fillers and films for wound healing applications. Silver ions doped HA were examined using EPR for better biocompatibility. These findings further aim to create a patient-specific implant using 3D modelling. It paves the way for the potential applications as a pre-operative surgical planning procedure and a better point of health care. Further, the biominerals extracted would act as a source for the fabrication of designs and thereafter 3D modelling for investigation. It also rectifies tissue engineering challenges faced so far.


hydroxyapatite seashells composite scaffold bone tissue engineering

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How to Cite
Renganathan, G., Dheivanai, R., Durai, K., & Lakshmi Madurai, S. (2022). Novel Bio-fabrication Modelling Approach from Marine Sources: Synthesis, Characterization and its Composite Formulations. Trends in Biomaterials & Artificial Organs, 36(S1), 59-66. Retrieved from