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Bone is an interesting and intriguing tissue, which is highly adaptable and shows specific response to the placement of biomaterials in its vicinity. Replacement and reconstruction of bone has been attempted since time immemorial. In the recent years, the number of materials used for bone reconstruction has been on the rise. Especially, long term replacement and augmentation of bone using rigid materials are gaining focus. At every point of time, there occurs a necessity to review the trends in such rapidly changing areas of research. Hence, this review analyses the phenomenon and the materials showing biointegration. The analysis is begun with a modest insight into surface modifications and proceeded further with biointegrative materials made of  metals, ceramics and polymers/composites. A decent attempt is made to analyse all the existing non resorbable bone biomaterials. The discussion is concluded with an insight into nanotechnology for biointegration.

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How to Cite
Raghavan, N., & Sastry, T. (2014). Biointegration to Bone – Current Concepts and Perspectives. Trends in Biomaterials & Artificial Organs, 28(3), 113-120. Retrieved from