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In recent years, the bone disorder diseases are becoming very common in which hydroxyapatite (HAP) has been a promising material for the bone regeneration and repairing hard tissues. The addition of polymers strengthens the mechanical stability and also favours in bone regeneration. The use of natural polymers is favoured by excellent biocompatibility and low toxicity. Even though polymer-hydroxyapatite composite has many advantages, certain properties like low tensile and mechanical strength, etc., limits its use in biomedical applications. Graphene oxide (GO) has been a promising material in diverse applications. The nano hydroxyapatite was prepared using precipitation method followed by sintering and graphene oxide using modified hummers method respectively. The surface structure recorded using Optical imaging and Scanning Electron Microscope (SEM). The functional groups present in the bioceramic polymer composite were characterised with FTIR and the crystalline properties with XRD. The bone growth and biocompatibility of the prepared composites were evaluated using the Simulated Body fluid (SBF), Tris HCL buffer for a period of 14 and 7 days respectively.


hydroxyapatite graphene oxide simulated body fluid immersion studies

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Ganeasan, M. S., Veerabadran, K., & Sridhar*, T. (2021). Green Synthesis Assisted Hydroxyapatite-Graphene Oxide Composite-An Effective Carrier for Drug Delivery and Bone Regeneration . Trends in Biomaterials & Artificial Organs, 35(5), 454-460. Retrieved from