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Abstract

Biomimetics is a well-known concept of abstraction and application of biological principles into human-made technologies in general and materials science and technology, in particular. In the last decade of the 20th century, when the term biomimetics was still a new concept in the field of materials science and engineering, our research group at CSIR-National Metallurgical Laboratory (CSIR-NML) started its biomimetic research journey. CSIR-NML team developed innovative synthesis routes to produce nanoparticles with controlled nucleation and growth, yielding nanostructures of different materials, namely, copper, iron oxides, cadmium sulfides, calcium carbonate etc. A natural flow of our work brought us to the domain of biomimetic bone grafts of different forms, including osteoconductive nano-powders, injectable bioceramic pastes and osteoinductive 3D scaffolds for non-load bearing and load bearing bone application. Recognizing the importance of high strength biocompatible and biodegradable metallic alloys for load bearing orthopedic applications, our group is presently involved in developing high strength Mg and Zn based biodegradable alloys. Our current research efforts are directed towards controlling the degradation rate of the developed Mg alloys to the desired level by suitable surface modification techniques to make it a viable industrial product for the biomaterial sector. Our research journey, in the field of biomaterials, became more interesting and productive with the active participation of the biomaterial industries of India. The present manuscript briefly reports some of the significant contributions made by the biomaterial research group at CSIR-NML in the field of biomimetic nanocomposites and biodegradable alloys for possible biomedical application.

Keywords

biomimetic nanocomposite hydroxyapatite biodegradable alloy orthopedic implants

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How to Cite
Sinha*, A., Sarkar, C., Guha, A., & Kaliath, A. J. (2021). Biomaterials: An Ongoing Journey from Biomimetics to Biodegradable Alloys. Trends in Biomaterials & Artificial Organs, 35(5), 471-477. Retrieved from https://www.biomaterials.org.in/tibao/index.php/tibao/article/view/528

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