Traditional to Advanced Wound Care: Classification, Healing Stages, and Technological Progress: A Comprehensive Review
DOI:
https://doi.org/10.65795/ezjwzz72Keywords:
wound healing, wound dressing, hydrocolloids, hydrogels, nanoscaffolds, nanoparticle based dressingAbstract
Effective wound care management necessitates thorough knowledge of wounds, their classification and appropriate treatment strategies to promote optimal wound healing. Wounds are categorised based on exposure to the environment, recovery time and contamination. These classifications aid healthcare professionals in selecting appropriate strategic treatment approaches and choosing suitable wound dressings to support rapid wound healing. Cotton gauze, bandages, plasters, and lint have traditionally served as wound care dressings. They primarily functioned as protective barriers that covered the wound but failed to maintain a moist environment, often resulting in direct adhesive contact with the wound surface, required frequent changes of wound dressings, and contributed to serious infection risk. To overcome these challenges, technological advancements have been incorporated into wound care materials, such as foam dressings, film dressings, hydrocolloids, hydrogels, nanoscaffolds, and nanoparticle-based dressings, to hasten the wound healing process. This article reviews types of wounds based on exposure to the environment, recovery time, and contamination, as well as conventional methods of wound management and recent innovations in dressing materials, highlighting their importance in enhancing healing processes and improving overall patient care.
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M Rodrigues, N Kosaric, CA Bonham, GC Gurtner. Wound healing: A cellular perspective. Physiol Rev. 2019;99(1):665–706. DOI: https://doi.org/10.1152/physrev.00067.2017
AA Mamun, C Shao, P Geng, S Wang, J Xiao. Recent advances in molecular mechanisms of skin wound healing and its treatments. Front Immunol. 2024;15:1395479. DOI: https://doi.org/10.3389/fimmu.2024.1395479
YH Almadani, J Vorstenbosch, PG Davison, AM Murphy. Wound healing: A comprehensive review. Semin Plast Surg. 2021;35(3):141–144. DOI: https://doi.org/10.1055/s-0041-1731791
Chhabra S, Chhabra N, Kaur A, Gupta N. Wound healing concepts in clinical practice of OMFS. J Maxillofac Oral Surg. 2017;16(4):403–423. DOI: https://doi.org/10.1007/s12663-016-0880-z
S Guo, LA DiPietro. Factors affecting wound healing. J Dent Res. 2010;89(3):219–229. DOI: https://doi.org/10.1177/0022034509359125
NR Raju, E Silina, V Stupin, N Manturova, SB Chidambaram, RR Achar. Multifunctional and smart wound dressings—A review on recent research advancements in skin regenerative medicine. Pharmaceutics. 2022;14(8):1574. DOI: https://doi.org/10.3390/pharmaceutics14081574
M Mirhaj, S Labbaf, M Tavakoli, AM Seifalian. Emerging treatment strategies in wound care. Int Wound J. 2022;19(7):1934–1954. DOI: https://doi.org/10.1111/iwj.13786
C Shi, C Wang, H Liu, Q Li, R Li, Y Zhang, Y Liu, Y Shao, J Wang. Selection of appropriate wound dressing for various wounds. Front Bioeng Biotechnol. 2020;8:182. DOI: https://doi.org/10.3389/fbioe.2020.00182
S Dhivya, VV Padma, E Santhini. Wound dressings – A review. BioMedicine. 2015;5(4):22.
E Rezvani Ghomi, S Khalili, S Nouri Khorasani, R Esmaeely Neisiany, S Ramakrishna. Wound dressings: Current advances and future directions. J Appl Polym Sci. 2019;136(27):47738. DOI: https://doi.org/10.1002/app.47738
LIF Moura, AMA Dias, E Carvalho, HC de Sousa. Recent advances on the development of wound dressings for diabetic foot ulcer treatment—A review. Acta Biomater. 2013;9(7):7093–7114. DOI: https://doi.org/10.1016/j.actbio.2013.03.033
RG Frykberg, J Banks. Challenges in the treatment of chronic wounds. Adv Wound Care. 2015;4(9):560–582. DOI: https://doi.org/10.1089/wound.2015.0635
JE Grey, S Enoch, KG Harding. ABC of wound healing: wound assessment. BMJ. 2006;332(7536):285–288. DOI: https://doi.org/10.1136/bmj.332.7536.285
RF Edlich, GT Rodeheaver, RF Morgan, DE Berman, JG Thacker. Principles of emergency wound management. Ann Emerg Med. 1988;17(12):1284–1302. DOI: https://doi.org/10.1016/S0196-0644(88)80354-8
GA Gresham. Wounds. In: Colour atlas of wounds and wounding. Dordrecht: Springer; 1984. p. 9–27. DOI: https://doi.org/10.1007/978-94-009-4123-6_1
AL King, MS Finnin, CM Kramer. Significance of open wounds potentially caused by non-lethal weapons. Institute for Defense Analyses; 2019.
JD Whitney. Overview: Acute and chronic wounds. Nurs Clin North Am. 2005;40(2):191–205. DOI: https://doi.org/10.1016/j.cnur.2004.09.002
N Bhagavathula, RL Warner, M DaSilva, SD McClintock, A Barron, MN Aslam, KJ Johnson, J Varani. A combination of curcumin and ginger extract improves abrasion wound healing in corticosteroid-impaired hairless rat skin. Wound Repair Regen. 2010;17(3):360. DOI: https://doi.org/10.1111/j.1524-475X.2009.00483.x
MI Maqsood. Classification of wounds: Know before research and clinical practice. J Genes Cells. 2018;4(1):1–4. DOI: https://doi.org/10.15562/gnc.61
NJ Percival. Classification of wounds and their management. Surgery. 2002;20(5):114–117. DOI: https://doi.org/10.1383/surg.20.5.114.14626
AK Gupta, A Shemer, V Economopoulos, M Talukder. Diabetic foot and fungal infections: Etiology and management from a dermatologic perspective. J Fungi (Basel). 2024;10(8):577. DOI: https://doi.org/10.3390/jof10080577
H Brem, J Balledux, T Bloom, et al. Healing of diabetic foot ulcers and pressure ulcers with human skin equivalent: A new paradigm in wound healing. Arch Surg. 2000;135(6):627–634. DOI: https://doi.org/10.1001/archsurg.135.6.627
DL Krasner DL, editor. Chronic wound care: A clinical source book for healthcare professionals. 5th ed. Vol. 1. HMP Global Learning Network; 2018.
TF Herman TF, P Popowicz, B Bordoni. Wound classification. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2023.
KS Midwood, LV Williams, JE Schwarzbauer. Tissue repair and the dynamics of the extracellular matrix. Int J Biochem Cell Biol. 2004;36(6):1031–1037. DOI: https://doi.org/10.1016/j.biocel.2003.12.003
F Yang, X Bai, X Dai, Y Li. The biological processes during wound healing. Regen Med. 2021;16(4):373–390. DOI: https://doi.org/10.2217/rme-2020-0066
H Sorg, DJ Tilkorn, S Hager, J Hauser, U Mirastschijski. Skin wound healing: An update on the current knowledge and concepts. Eur Surg Res. 2017;58(1–2):81–94. DOI: https://doi.org/10.1159/000454919
NN Potekaev, OB Borzykh, GV Medvedev, DV Pushkin, MM Petrova, AV Petrov, DV Dmitrenko, EI Karpova, OM Demina, NA Shnayder. The role of extracellular matrix in skin wound healing. J Clin Med. 2021;10(24):5947. DOI: https://doi.org/10.3390/jcm10245947
CL Theoret. Tissue engineering in wound repair: The three “R”s—Repair, replace, regenerate. Vet Surg. 2009;38(8):905–913. DOI: https://doi.org/10.1111/j.1532-950X.2009.00585.x
G Han , R Ceilley. Chronic wound healing: A review of current management and treatments. Adv Ther. 2017;34(3):599–610. DOI: https://doi.org/10.1007/s12325-017-0478-y
MH Periayah, AS Halim, AZM Saad. Mechanism action of platelets and crucial blood coagulation pathways in hemostasis. Int J Hematol Oncol Stem Cell Res. 2017;11(4):319–327.
J Li, J Chen, RS Kirsner. Pathophysiology of acute wound healing. Clin Dermatol. 2007;25(1):9–18. DOI: https://doi.org/10.1016/j.clindermatol.2006.09.007
M Ansari, A Darvishi. A review of the current state of natural biomaterials in wound healing applications. Front Bioeng Biotechnol. 2024;12:1309541. DOI: https://doi.org/10.3389/fbioe.2024.1309541
J Rajkumar, N Chandan, P Lio, V Shi. The skin barrier and moisturization: Function, disruption, and mechanisms of repair. J Dermatolog Treat. 2023;36(4):174–185. DOI: https://doi.org/10.1159/000534136
G Broughton II, JE Janis, CE Attinger. The basic science of wound healing. Plast Reconstr Surg. 2006;117(7 Suppl):12S–34S. DOI: https://doi.org/10.1097/01.prs.0000225430.42531.c2
S Singh, A Young, CE McNaught. The physiology of wound healing. Surgery (Oxford). 2017;35(9):473–477. DOI: https://doi.org/10.1016/j.mpsur.2017.06.004
Prasetyono TOH. General concept of wound healing, revisited. Med J Indones. 2009;18:208–216. DOI: https://doi.org/10.13181/mji.v18i3.364
FN Rosyid. Wounds: Physiological mechanisms and factors affecting healing. Int J Res Med Sci. 2022;10(4):1001–1006. DOI: https://doi.org/10.18203/2320-6012.ijrms20221000
MP Rodero, K Khosrotehrani. Skin wound healing modulation by macrophages. Int J Clin Exp Pathol. 2010;3(7):643–653.
AW Ho, TS Kupper. T cells and the skin: From protective immunity to inflammatory skin disorders. Nat Rev Immunol. 2019;19:490–502. DOI: https://doi.org/10.1038/s41577-019-0162-3
ACO Gonzalez, TF Costa, ZN Andrade, ARF Medrado. Wound healing – A literature review. An Bras Dermatol. 2016;91(5):614–620. DOI: https://doi.org/10.1590/abd1806-4841.20164741
JV Vicente-da-Silva, JOSL Pereira, FA do Carmo, BFC Patricio. Skin and wound healing: Conventional dosage versus nanobased emulsions forms. ACS Omega. 2025;10(13):12837–12855. DOI: https://doi.org/10.1021/acsomega.5c00455
P Monika, MN Chandraprabha, A Rangarajan, PV Waiker, KN Chidambara Murthy. Challenges in healing wound: Role of complementary and alternative medicine. Front Nutr. 2022;8:791899. DOI: https://doi.org/10.3389/fnut.2021.791899
D Okan, K Woo, EA Ayello, RG Sibbald. The role of moisture balance in wound healing. Adv Skin Wound Care. 2007;20(1):39–53. DOI: https://doi.org/10.1097/00129334-200701000-00013
K Jonsson, JA Jensen, WH Goodson III, H Scheuenstuhl, J West, HW Hopf, TK Hunt. Tissue oxygenation, anemia, and perfusion in relation to wound healing in surgical patients. Ann Surg. 1991;214(5):605–613. DOI: https://doi.org/10.1097/00000658-199111000-00011
P Dave. The challenges of chronic wound care and management. Asian J Dent Health Sci. 2024;4(1):45–50. DOI: https://doi.org/10.22270/ajdhs.v4i1.70
HC Horng, WH Chang, CC Yeh, BS Huang, CP Chang, YJ Chen, KH Tsui, PH Wang. Estrogen effects on wound healing. Int J Mol Sci. 2017;18(11):2325. DOI: https://doi.org/10.3390/ijms18112325
SC Gilliver, JJ Ashworth, GS Ashcroft. The hormonal regulation of cutaneous wound healing. Clin Dermatol. 2007;25(1):56–62. DOI: https://doi.org/10.1016/j.clindermatol.2006.09.012
RT Beyene, SL Derryberry, A Barbul. The effect of comorbidities on wound healing. Surg Clin North Am. 2020;100(4):695–705. DOI: https://doi.org/10.1016/j.suc.2020.05.002
YC Boo. Ascorbic acid (vitamin C) as a cosmeceutical to increase dermal collagen for skin antiaging purposes: Emerging combination therapies. Antioxidants (Basel). 2022;11(9):1663. DOI: https://doi.org/10.3390/antiox11091663
CS Rosenberg. Wound healing in the patient with diabetes mellitus. Nurs Clin North Am. 1990;25(1):247–261. DOI: https://doi.org/10.1016/S0029-6465(22)00238-9
DG Greenhalgh. Wound healing and diabetes mellitus. Clin Plast Surg. 2003;30(1):37–45. DOI: https://doi.org/10.1016/S0094-1298(02)00066-4
H Brem, M Tomic-Canic. Cellular and molecular basis of wound healing in diabetes. J Clin Invest. 2007;117(5):1219–1222. DOI: https://doi.org/10.1172/JCI32169
KY Woo, RG Sibbald. Chronic wound pain: A conceptual model. Adv Skin Wound Care. 2008;21(4):175–188. DOI: https://doi.org/10.1097/01.ASW.0000305430.01413.2e
A Takahashi, ME Flanigan, BS McEwen, SJ Russo. Aggression, social stress, and the immune system in humans and animal models. Front Behav Neurosci. 2018;12:56. DOI: https://doi.org/10.3389/fnbeh.2018.00056
CR Gordon, Y Rojavin, M Patel, JE Zins, G Grana, B Kann, R Simons, U Atabek. A review on bevacizumab and surgical wound healing: An important warning to all surgeons. Ann Plast Surg. 2009;62(6):707–709. DOI: https://doi.org/10.1097/SAP.0b013e3181828141
LT Sørensen, S Jørgensen, LJ Petersen, U Hemmingsen, J Bulow, S Loft, F Gottrup. Acute effects of nicotine and smoking on blood flow, tissue oxygen, and aerobic metabolism of the skin and subcutis. J Surg Res. 2009;152(2):224–230. DOI: https://doi.org/10.1016/j.jss.2008.02.066
EH Manassa, CH Hertl, RR Olbrisch. Wound healing problems in smokers and nonsmokers after 132 abdominoplasties. Plast Reconstr Surg. 2003;111(6):2082–2087. DOI: https://doi.org/10.1097/01.PRS.0000057144.62727.C8
TR Beahrs, J Reagan, CC Bettin, BJ Grear, GA Murphy, DR Richardson. Smoking effects in foot and ankle surgery: An evidence-based review. Foot Ankle Int. 2019;40(10):1226–1232. DOI: https://doi.org/10.1177/1071100719867942
E Avishai, K Yeghiazaryan, O Golubnitschaja. Impaired wound healing: Facts and hypotheses for multi-professional considerations in predictive, preventive and personalized medicine. EPMA J. 2017;8(1):23–33. DOI: https://doi.org/10.1007/s13167-017-0081-y
M de Wit, S Goldberg, E Hussein, JP Neifeld. Health care-associated infections in surgical patients undergoing elective surgery: Are alcohol use disorders a risk factor? J Am Coll Surg. 2012;215(2):229–236. DOI: https://doi.org/10.1016/j.jamcollsurg.2012.04.015
MJ Ranzer, L Chen, LA DiPietro. Fibroblast function and wound breaking strength is impaired by acute ethanol intoxication. Alcohol Clin Exp Res. 2011;35(1):83–90. DOI: https://doi.org/10.1111/j.1530-0277.2010.01324.x
AS Montaser, M Rehan, WM El-Senousy, S Zaghloul. Designing strategy for coating cotton gauze fabrics and its application in wound healing. Carbohydr Polym. 2020;244:116479. DOI: https://doi.org/10.1016/j.carbpol.2020.116479
MP Mani, AAM Faudzi, S Ramakrishna, AF Ismail, SK Jaganathan, N Tucker, R Rathanasamy. Sustainable electrospun materials with enhanced blood compatibility for wound healing applications—A mini review. Curr Opin Biomed Eng. 2023;26:100457. DOI: https://doi.org/10.1016/j.cobme.2023.100457
S Dhivya, VV Padma, E Santhini. Wound dressings – A review. BioMedicine. 2015;5(4):22. DOI: https://doi.org/10.7603/s40681-015-0022-9
VE Jones. Alternative antimicrobial approaches to fighting multidrug resistant infections. In: Fighting multidrug resistance with herbal extracts, essential oils and their components. 2025. p. 3–18. DOI: https://doi.org/10.1016/B978-0-443-29044-2.00002-3
RK Chalannavar, MS Divakar, A Kumar, RB Malabadi, AA Swathi, Kamble, KS Karamchand, KP Kolkar, S Moramazi, ANR Munhoz, KVC Coronado. Wound healing: Traditional plant based and modern wound dressing—An update. Int J Biol Pharm Sci Arch. 2025;9(2):44–66. DOI: https://doi.org/10.53771/ijbpsa.2025.9.2.0039
SD Bhoyar, K Malhotra, B Madke. Dressing materials: A comprehensive review. J Cutan Aesthet Surg. 2023;16(2):81–89. DOI: https://doi.org/10.4103/JCAS.JCAS_163_22
JS Boateng, KH Matthews, HNE Stevens, GM Eccleston. Wound healing dressings and drug delivery systems: A review. J Pharm Sci. 2008;97(8):2892–2923. DOI: https://doi.org/10.1002/jps.21210
VJ Jones VJ. The use of gauze: Will it ever change? Int Wound J. 2006;3(2):79–86. DOI: https://doi.org/10.1111/j.1742-4801.2006.00215.x
N Gokarneshan. Some significant developments in bandage fabrics. J Nurs Patient Health Care. 2019;1(1):104. DOI: https://doi.org/10.15744/2767-9292.1.104
P Zahedi, I Rezaeian, SM Ranaei-Siadat, SH Jafari, P Supaphol. A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages. Polym Adv Technol. 2010;21(2):77–95.
P Zahedi, I Rezaeian, SM Ranaei-Siadat, SH Jafari, P Supaphol. A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages. Polym Adv Technol. 2010;21(2):77–95. DOI: https://doi.org/10.1002/pat.1625
R Clarke. Plaster technique. In: War surgery of the extremities. BMJ. 1942;1(4251):797–800. DOI: https://doi.org/10.1136/bmj.1.4251.797
M DeMaio, K McHale, M Lenhart, J Garland, C McIlvaine, M Rhode. Plaster: Our orthopaedic heritage: AAOS exhibit selection. J Bone Joint Surg Am. 2012;94(20):e152. DOI: https://doi.org/10.2106/JBJS.L.00183
L Ovington. The art and science of wound dressings in the twenty first century. In: Falabella AF, Kirsner RS, editors. Wound healing. Taylor & Francis/CRC Press; 2005. p. 72–87.
V Jones, JE Grey, KG Harding. ABC of wound healing: Wound dressings. BMJ. 2006;332:777–780. DOI: https://doi.org/10.1136/bmj.332.7544.777
A Punjataewakupt, P Aramwit. Wound dressing adherence: A review. J Wound Care. 2022;31(5):406–423. DOI: https://doi.org/10.12968/jowc.2022.31.5.406
E Rezvani Ghomi, M Niazi, S Ramakrishna. The evolution of wound dressings: From traditional to smart dressings. Polym Adv Technol. 2023;34(2):520–530. DOI: https://doi.org/10.1002/pat.5929
A Hargis, M Yaghi, NM Bermudez, A Gefen. Foam dressings for wound healing. Curr Dermatol Rep. 2024;13(1):28–35. DOI: https://doi.org/10.1007/s13671-024-00422-2
P Chaganti, I Gordon, JH Chao, S Zehtabchi. A systematic review of foam dressings for partial thickness burns. Am J Emerg Med. 2019;37(6):1184–1190. DOI: https://doi.org/10.1016/j.ajem.2019.04.014
JK Park, JH Lee, JJ Kwak, HB Shin, HW Jung, SW Bae, et al. Evaluation of an antimicrobial silver foam dressing. Wounds. 2013;25(6):153–159.
K Sillmon, C Moran, L Shook, C Lawson, AH Burfield. The use of prophylactic foam dressings for prevention of hospital-acquired pressure injuries: a systematic review. J Wound Ostomy Continence Nurs. 2021;48(3):211–218. DOI: https://doi.org/10.1097/WON.0000000000000762
J Nielsen, K Fogh. Clinical utility of foam dressings in wound management: a review. Chronic Wound Care Manag Res. 2015;2:31–38. DOI: https://doi.org/10.2147/CWCMR.S50832
RM Walker, BM Gillespie, L Thalib, NS Higgins, JA Whitty. Foam dressings for treating pressure ulcers. Cochrane Database Syst Rev. 2017;(10):CD011332. DOI: https://doi.org/10.1002/14651858.CD011332.pub2
S Thomas, V Banks, M Fear, S Hagelstein, S Bale, K Harding. A study to compare two film dressings used as secondary dressings. J Wound Care. 1997;6(7):333–336. doi:10.12968/jowc.1997.6.7.333. DOI: https://doi.org/10.12968/jowc.1997.6.7.333
HV Pawar, J Tetteh, JS Boateng. Preparation, optimisation and characterisation of novel wound healing film dressings loaded with streptomycin and diclofenac. Colloids Surf B Biointerfaces. 2013;102:102–110. DOI: https://doi.org/10.1016/j.colsurfb.2012.08.014
G Dabiri, E Damstetter, T Phillips. Choosing a wound dressing based on common wound characteristics. Adv Wound Care. 2016;5(1):32–41. DOI: https://doi.org/10.1089/wound.2014.0586
SF Bernatchez. Care of peripheral venous catheter sites: advantages of transparent film dressings over tape and gauze. J Assoc Vasc Access. 2014;19(4):256–261. DOI: https://doi.org/10.1016/j.java.2014.09.001
S Thomas. Hydrocolloid dressings in the management of acute wounds: a review of the literature. Int Wound J. 2008;5(5):602–613. DOI: https://doi.org/10.1111/j.1742-481X.2008.00541.x
B Lanel, D Barthès-Biesel, C Regnier, T Chauvé. Swelling of hydrocolloid dressings. Biorheology. 1997;34(2):139–153. DOI: https://doi.org/10.3233/BIR-1997-34205
JC Dumville, S Deshpande, S O’Meara, K Speak. Hydrocolloid dressings for healing diabetic foot ulcers. Cochrane Database Syst Rev. 2013;(8):CD009099. DOI: https://doi.org/10.1002/14651858.CD009099.pub3
SP Holmes, S Rivera, PB Hooper, JE Slaven, SKT Que. Hydrocolloid dressing versus conventional wound care after dermatologic surgery. JAAD Int. 2021;6:37–42. DOI: https://doi.org/10.1016/j.jdin.2021.11.002
A Francesko, P Petkova, T Tzanov. Hydrogel dressings for advanced wound management. Curr Med Chem. 2018;25(41):5782–5797. DOI: https://doi.org/10.2174/0929867324666170920161246
H Wang, Z Xu, M Zhao, G Liu, J Wu. Advances of hydrogel dressings in diabetic wounds. Biomater Sci. 2021;9(5):1530–1546. DOI: https://doi.org/10.1039/D0BM01747G
V Brumberg, T Astrelina, T Malivanova, A Samoilov. Modern wound dressings: hydrogel dressings. Biomedicines. 2021;9(10):1235. DOI: https://doi.org/10.3390/biomedicines9091235
JM Rosiak, F Yoshii. Hydrogels and their medical applications. Nucl Instrum Methods Phys Res B. 1999;151:56–64. DOI: https://doi.org/10.1016/S0168-583X(99)00118-4
B Dhandayuthapani, Y Yoshida, T Maekawa, DS Kumar. Polymeric scaffolds in tissue engineering application: a review. Int J Polym Sci. 2011;2011:290602. DOI: https://doi.org/10.1155/2011/290602
IR Calori, G Braga, PDC de Jesus, H Bi, AC Tedesco. Polymer scaffolds as drug delivery systems. Eur Polym J. 2020;129:109621. DOI: https://doi.org/10.1016/j.eurpolymj.2020.109621
H Yi, F Ur Rehman, C Zhao, B Liu, N He. Recent advances in nano scaffolds for bone repair. Bone Res. 2016;4:16050. DOI: https://doi.org/10.1038/boneres.2016.50
B Deepika, A Gopikrishna, A Girigoswami, M Nilofer Banu, K Girigoswami. Applications of nanoscaffolds in tissue engineering. Curr Pharmacol Rep. 2022;8:171–187. DOI: https://doi.org/10.1007/s40495-022-00284-x
C Xu, OU Akakuru, X Ma, J Zheng, J Zheng, A Wuat. Nanoparticle-based wound dressing: recent progress in the detection and therapy of bacterial infections. Bioconjug Chem. 2020;31(7):1708–1723. DOI: https://doi.org/10.1021/acs.bioconjchem.0c00297
L Jiang, SCJ Loo. Intelligent nanoparticle-based dressings for bacterial wound infections. ACS Appl Bio Mater. 2021;4(5):3849–3862. DOI: https://doi.org/10.1021/acsabm.0c01168
NK Rajendran, SSD Kumar, NN Houreld, H Abrahamse. A review on nanoparticle-based treatment for wound healing. J Drug Deliv Sci Technol. 2018;44:421–430. DOI: https://doi.org/10.1016/j.jddst.2018.01.009
M Berthet, Y Gauthier , C Lacroix, B Verrier, C Monge. Nanoparticle-based dressing: the future of wound treatment? Trends Biotechnol. 2017;35(8):770–784. DOI: https://doi.org/10.1016/j.tibtech.2017.05.005
F Strodtbeck. Physiology of wound healing. Newborn Infant Nurs Rev. 2001;1(1):43–52. DOI: https://doi.org/10.1053/nbin.2001.23176
LG Ovington. Advances in wound dressings. Clin Dermatol. 2007;25(1):33–38. DOI: https://doi.org/10.1016/j.clindermatol.2006.09.003
S O’Callaghan, P Galvin, C O’Mahony, Z Moore, R Derwin. ‘Smart’ wound dressings for advanced wound care: a review. J Wound Care. 2020;29(7):394–406. DOI: https://doi.org/10.12968/jowc.2020.29.7.394
PS Murphy, GRD Evans. Advances in wound healing: a review of current wound healing products. Plast Surg Int. 2012;2012:190436. DOI: https://doi.org/10.1155/2012/190436
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Accepted 24-06-2026
Published 09-07-2026
