Nanomaterials in Medical Imaging: Breakthroughs, Challenges, and Prospects

Authors

  • Dibyendu Mandal Department of Biomedical Engineering, JIS College of Engineering, Kalyani 741235, West Bengal, India Author
  • Kumaresh Halder Department of Basic Science and Humanities, Regent Education and Research Foundation, Barrackpore 700121, West Bengal India Author
  • Sandip Bag* Department of Biomedical Engineering, JIS College of Engineering, Kalyani 741235, West Bengal, India Author

Keywords:

contrast enhancement, medical imaging, nanomaterials, precision diagnostics, targeted imaging agents

Abstract

Nanomaterials have emerged as transformative agents in medical imaging by offering enhanced contrast, improved sensitivity, and multifunctionality. Their unique physicochemical properties enable superior performance in various imaging modalities, including MRI, CT, PET, SPECT. Recent advancements in nanotechnology have led to the development of targeted imaging agents with high specificity, enabling early disease detection and precision diagnostics. Real-time imaging and theranostics, especially in oncology and neurology, are made possible by advancements in smart and stimuli-responsive nanoplatforms. Despite these breakthroughs, challenges such as biocompatibility, toxicity, stability, and regulatory hurdles remain significant obstacles to clinical translation. This paper explores the latest advancements in nanomaterials for medical imaging, highlighting their state-of-the-art applications, ongoing challenges, and prospects. The integration of nanotechnology with artificial intelligence and personalized medicine is expected to further revolutionize the field, paving the way for next-generation potent diagnostic tools that improve patient outcomes and enhance the accuracy of medical imaging techniques.

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Author Biographies

  • Dibyendu Mandal, Department of Biomedical Engineering, JIS College of Engineering, Kalyani 741235, West Bengal, India

    Department of Biomedical Engineering, Assistant Professor

  • Kumaresh Halder, Department of Basic Science and Humanities, Regent Education and Research Foundation, Barrackpore 700121, West Bengal India

    Department of Basic Science and Humanities, Assistant Professor

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Published

28-10-2025

Issue

Section

Review Article

How to Cite

Nanomaterials in Medical Imaging: Breakthroughs, Challenges, and Prospects. (2025). Trends in Biomaterials and Artificial Organs, 39(4), 342-351. https://www.biomaterials.org.in/tibao/index.php/tibao/article/view/166
Received 17-07-2025
Accepted 11-10-2025
Published 28-10-2025