A Review Nanotechnology Based Approaches for Carcinogenesis Treatment: A Review

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Kuljeet Kaur Anand Mohan Madhuri Girdhar

Abstract

ABSTRACT


Cancer, a dreadful disease is the great trouble for the recent generations that does not have any limits and can thus affect any type of organ in the person’s body. It is one of the most dangerous disease that can destroy many millions of people life in the whole world per year. Carcinogenesis ultimately leads to formation of malignant mass, which may result in progressive cell differentiation that relates with the ongoing changes or moderations at the cellular, genetic and epigenetic levels. For the treatment of cancer, a diverse variety of approaches have been executed, which consist of some significance, limitations and after effects. Conventional chemotherapy is a familiar technique which is used to deliver the anticancerous agents to patient’s body consists of rapid proliferation of the cancer cells.But unluckily, due to the non-specific targeting therapies by anticancerous drugs may cause major aftereffects on normal healthy cells and  non-specific drug delivery cannot bring the desired outcomes. The difficult task in the treatment of cancer therapeutics is to distinguish the cancerous cells from the normal body cells. Nanotechnology is the technology of science which is mainly concerned with the size of nanoparticles that ranges from small nanometers (nm) scale to several hundred nanometers (nm). Nanotechnology has been the area of interest of many scientists and researchers for the enhancing accurate drug delivery system over the last decades,as thisprovides diverse advantages to overwhelm the limitations that are arising in traditional methods for the treatment of cancer. Cancer nanotechnology is being enthusiastically evaluated and implemented in cancer treatment and major emphasis is given for the development of polymer based controlled drug delivery applications. Many natural polymers are being utilized for targeted drug delivery as it shows unique characteristic features i.e. biodegradable, biocompatible, non-immunotoxic, non-inflammatory, time-controlled drug delivery, large surface area and high efficacy. All these features show effective therapeutic applications of polymers in cancer research studies.

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Review Articles